Name | Glutathione peroxidase 2 | ||
UniProt ID | GPX2_HUMAN | ||
Gene Name | GPX2 | ||
Gene ID | 2877 | ||
Synonyms |
GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2
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Sequence |
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR
LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP DIKRLLKVAI |
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Pathway Map | MAP LINK | ||
KEGG ID | hsa2877 | ||
Pfam | PF00255; PF08534 |
Pair Name | All-trans retinoic acid, Decitabine | |||
Phytochemical | All-trans-retinoic acid | |||
Drug | Decitabine | |||
Disease Info | [ICD-11: 2A60.Z] | Acute myeloid leukemia | Investigative | |
Regulate Info | Down-regulation | Glutathione peroxidase 2 | Expression | |
Result | These results demonstrate that combining DAC and ATRA has potential for the clinical treatment of HR-MDS/AML and merits further exploration. |