| Name | FUN14 domain-containing protein 1 | ||
| UniProt ID | FUND1_HUMAN | ||
| Gene Name | FUNDC1 | ||
| Gene ID | 139341 | ||
| Synonyms |
FUNDC1
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| Sequence |
MATRNPPPQDYESDDDSYEVLDLTEYARRHQWWNRVFGHSSGPMVEKYSVATQIVMGGVT
GWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKA APEINNLIEEATEFIKQNIVISSGFVGGFLLGLAS |
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| Pathway Map | MAP LINK | ||
| KEGG ID | hsa139341 | ||
| Pfam | PF04930; PF06277; PF09769 | ||
| Pair Name | Artesunate, Sorafenib | |||
| Phytochemical | Artesunate | |||
| Drug | Sorafenib | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Down-regulation | FUN14 domain-containing protein 1 | Phosphorylation | |
| Result | Artesunate may be a promising strategy to mitigate sorafenib resistance in HCC via exacerbating AFAP1L2-SRC-FUNDC1 axis-dependent mitophagy. | |||
