| Name | Dual specificity protein phosphatase 1 | ||
| UniProt ID | DUS1_HUMAN | ||
| Gene Name | DUSP1 | ||
| Gene ID | 1843 | ||
| Synonyms |
DUSP1, CL100, HVH1, MKP-1, MKP1, PTPN10
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| Sequence |
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAM
GLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFF LKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPF LYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEA IDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFS FMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSP ITTSPSC |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 9.A.14.13.44 | ||
| KEGG ID | hsa1843 | ||
| TTD ID | T35194 | ||
| Pfam | PF00102; PF00581; PF00782; PF04179; PF14566 | ||
| Pair Name | All-trans retinoic acid, Decitabine | |||
| Phytochemical | All-trans-retinoic acid | |||
| Drug | Decitabine | |||
| Disease Info | [ICD-11: 2A60.Z] | Acute myeloid leukemia | Investigative | |
| Regulate Info | Down-regulation | Dual specificity protein phosphatase 1 | Expression | |
| Result | These results demonstrate that combining DAC and ATRA has potential for the clinical treatment of HR-MDS/AML and merits further exploration. | |||
