| Name | Delta-like protein 3 | ||
| UniProt ID | DLL3_HUMAN | ||
| Gene Name | DLL3 | ||
| Gene ID | 10683 | ||
| Synonyms |
DLL3, SCDO1
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| Sequence |
MVSPRMSGLLSQTVILALIFLPQTRPAGVFELQIHSFGPGPGPGAPRSPCSARLPCRLFF
RVCLKPGLSEEAAESPCALGAALSARGPVYTEQPGAPAPDLPLPDGLLQVPFRDAWPGTF SFIIETWREELGDQIGGPAWSLLARVAGRRRLAAGGPWARDIQRAGAWELRFSYRARCEP PAVGTACTRLCRPRSAPSRCGPGLRPCAPLEDECEAPLVCRAGCSPEHGFCEQPGECRCL EGWTGPLCTVPVSTSSCLSPRGPSSATTGCLVPGPGPCDGNPCANGGSCSETPRSFECTC PRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRVDRCSLQ PCRNGGLCLDLGHALRCRCRAGFAGPRCEHDLDDCAGRACANGGTCVEGGGAHRCSCALG FGGRDCRERADPCAARPCAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAP PGLRPGDPQRYLLPPALGLLVAAGVAGAALLLVHVRRRGHSQDAGSRLLAGTPEPSVHAL PDALNNLRTQEGSGDGPSSSVDWNRPEDVDPQGIYVISAPSIYAREVATPLFPPLHTGRA GQRQHLLFPYPSSILSVK |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 8.A.68.1.14 | ||
| KEGG ID | hsa10683 | ||
| TTD ID | T75716 | ||
| Pfam | PF00008; PF01414; PF07657; PF07974; PF12661; PF12662; PF21195; PF21700 | ||
| Pair Name | Epigallocatechin gallate, Doxorubicin | |||
| Phytochemical | Epigallocatechin gallate | |||
| Drug | Doxorubicin | |||
| Disease Info | [ICD-11: 2B51] | Osteosarcoma | Investigative | |
| Regulate Info | Down-regulation | Delta-like protein 3 | Activity | |
| Result | SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition | |||
