Name | Protein Cripto | ||
UniProt ID | TDGF1_HUMAN | ||
Gene Name | CRIPTO | ||
Gene ID | 6997 | ||
Synonyms |
CRIPTO, CR, CR-1, CRGF, TDGF1
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Sequence |
MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIR
PRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPH DTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGI CLSIQSYY |
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Pathway Map | MAP LINK | ||
T.C. Number | 1.A.10.1.28; 3.A.1.201.1 | ||
KEGG ID | hsa6997 | ||
TTD ID | T47864 | ||
Pfam | PF00008; PF07974; PF09443; PF12661 |
Pair Name | Luteolin, Paclitaxel | |||
Phytochemical | Luteolin | |||
Drug | Paclitaxel | |||
Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
Regulate Info | Down-regulation | Protein Cripto | Expression | |
Result | These findings suggest that luteolin treatment significantly attenuated the hallmarks of breast cancer stemness by downregulating Nrf2-mediated expressions. Luteolin constitutes a potential agent for use in cancer stemness-targeted breast cancer treatments. |