| Name | Claudin-5 | ||
| UniProt ID | CLD5_HUMAN | ||
| Gene Name | CLDN5 | ||
| Gene ID | 7122 | ||
| Synonyms |
CLDN5, AWAL, BEC1, CPETRL1, TMDVCF, TMVCF
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| Sequence |
MTRARIGCFGPGGRARGTESAPEPSKRVPPGRSWQTQEVRQTRGANGLGPRAGSAGAKAP
GPAQGAAQHGLGGSAGLRVRVSPLAMGSAALEILGLVLCLVGWGGLILACGLPMWQVTAF LDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVAL FVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVS QKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKK NYV |
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| Pathway Map | MAP LINK | ||
| T.C. Number | 1.H.1.1.16 | ||
| KEGG ID | hsa7122 | ||
| Pfam | PF00822; PF07062; PF13903 | ||
| Pair Name | Tanshinone IIA, Anti-mouse PD-1 | |||
| Phytochemical | Tanshinone IIA | |||
| Drug | Anti-mouse PD-1 | |||
| Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
| Regulate Info | Up-regulation | Claudin-5 | Expression | |
| Result | This study reveals a new mechanism between TSA and ELTD1 for vascular normalization, suggesting that therapeutic or pharmacological intervention with ELTD1 may enhance the efficacy of PD-1 inhibitors in HCC. | |||
