| Drug Name |
Sildenafil
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| Synonyms |
sildenafil; 139755-83-2; VIAGRA; Sildenafil [INN:BAN]; UK-92480; UNII-3M7OB98Y7H; UK-92,480-10; C22H30N6O4S; HSDB 7305; CHEMBL192; UK 92480-10; CHEBI:9139; 3M7OB98Y7H; BNRNXUUZRGQAQC-UHFFFAOYSA-N; Sildenafil
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| Drug Type |
Small molecular drug
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| Indications |
Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y]
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Phase 3
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|
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Erectile dysfunction [ICD-11: HA01.1]
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Approved
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| Company |
NA
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| Summary |
Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
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| Target |
HUMAN phosphodiesterase type 5 (PDE5)
Mechanism of Action: Inhibitor
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T94879 | |
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Formula |
C22H30N6O4S
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| Canonical SMILES |
CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
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| InChI |
1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
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| InChIKey |
BNRNXUUZRGQAQC-UHFFFAOYSA-N
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| CAS Number | CAS 139755-83-2 | |
| TTD ID | D05ULR | |
| DrugBank ID | DB00203 | |
| PubChem Compound ID | 135398744 | |
| PubChem Substance ID |
NA
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| ChEBI ID | CHEBI:9139 | |
| ADReCS Drug ID | NA |
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |