Drug General Information

Drug Name
Sildenafil
Synonyms
sildenafil; 139755-83-2; VIAGRA; Sildenafil [INN:BAN]; UK-92480; UNII-3M7OB98Y7H; UK-92,480-10; C22H30N6O4S; HSDB 7305; CHEMBL192; UK 92480-10; CHEBI:9139; 3M7OB98Y7H; BNRNXUUZRGQAQC-UHFFFAOYSA-N; Sildenafil
Drug Type
Small molecular drug
Indications
Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y]
Phase 3
Erectile dysfunction [ICD-11: HA01.1]
Approved
Company
NA
Summary
Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
Target
HUMAN phosphodiesterase type 5 (PDE5)
Mechanism of Action: Inhibitor
T94879

Drug Chemical Infomation and External Links

Formula
C22H30N6O4S
Canonical SMILES
CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
InChI
1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey
BNRNXUUZRGQAQC-UHFFFAOYSA-N
CAS Number CAS 139755-83-2
TTD ID D05ULR
DrugBank ID DB00203
PubChem Compound ID 135398744
PubChem Substance ID
NA
ChEBI ID CHEBI:9139
ADReCS Drug ID NA

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification