Drug ID: D01040

Drug General Information

Drug Name
Selexipag
Synonyms
Selexipag; NS-304; 475086-01-2; Uptravi; NS 304; ACT-293987; UNII-5EXC0E384L; Selexipag(NS-304); ACT 293987; 5EXC0E384L; 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)-N-(methylsulfonyl)acetamide; 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide; 2-(4-((5,6-Diphenylpyrazin-2-yl)(propan-2-yl)amino)butoxy}-n-(methanesulfonyl)acetamide; Selexipag [USAN:INN]; 2-{4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butoxy}-N-(methanesulfonyl)acetamide; Uptravi (TN)
Drug Type
Small molecular drug
Indications
Pulmonary arterial hypertension [ICD-11: BB01.0]
Approved
Company
Actelion Pharmaceuticals
Summary
Selexipag is a non prostanoid IP prostacyclin receptor agonist used to treat pulmonary arterial hypertension.
Target
Prostacyclin receptor (PTGIR)
Mechanism of Action: Agonist
 T99954

Drug Chemical Infomation and External Links

Download MOL File
Formula
C26H32N4O4S
Canonical SMILES
CC(C)N(CCCCOCC(=O)NS(=O)(=O)C)C1=CN=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3
InChI
1S/C26H32N4O4S/c1-20(2)30(16-10-11-17-34-19-24(31)29-35(3,32)33)23-18-27-25(21-12-6-4-7-13-21)26(28-23)22-14-8-5-9-15-22/h4-9,12-15,18,20H,10-11,16-17,19H2,1-3H3,(H,29,31)
InChIKey
QXWZQTURMXZVHJ-UHFFFAOYSA-N
CAS Number CAS 475086-01-2
TTD ID D0N2SR
DrugBank ID DB11362
PubChem Compound ID 9913767
PubChem Substance ID
14884195 , 24193522 , 45985422 , 71826069 , 75827381 , 103543954 , 125335605 , 127344242 , 127344243 , 135268706 , 135626715 , 163125035 , 163893551 , 198953024 , 204362837 , 208265357 , 223365888 , 223872265 , 226969886 , 241376405 , 244974834 , 252157218 , 252228662 , 252480281
ChEBI ID CHEBI:90844
ADReCS Drug ID BADD_D02006

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification