Drug Name |
Rivaroxaban
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Synonyms |
XARELTO (TN)
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Drug Type |
Small molecular drug
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Indications |
Deep vein thrombosis [ICD-11: BD71]
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Approved
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Company |
Bayer HealthCare Pharmaceuticals; Johnson & Johnson Pharmaceutical Research & Development
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Summary |
Rivaroxaban is a factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
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Target |
Coagulation factor Xa (F10)
Mechanism of Action: Modulator
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T84631 |
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Formula |
C19H18ClN3O5S
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Canonical SMILES |
C1COCC(=O)N1C2=CC=C(C=C2)N3CC(OC3=O)CNC(=O)C4=CC=C(S4)Cl
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InChI |
1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
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InChIKey |
KGFYHTZWPPHNLQ-AWEZNQCLSA-N
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CAS Number | CAS 366789-02-8 | |
TTD ID | D0KG3R | |
DrugBank ID | DB06228 | |
PubChem Compound ID | 9875401 | |
PubChem Substance ID |
14856850
,
15279667
,
22395270
,
24164597
,
45622373
,
46513422
,
51091428
,
52936629
,
56373953
,
57373622
,
71825413
,
87225360
,
87557471
,
91615930
,
93580340
,
99444948
,
103469795
,
109693118
,
126659499
,
126666963
,
134342998
,
134358083
,
135213418
,
135684125
,
136375511
,
136920411
,
137128738
,
139479843
,
152258851
,
152344334
,
160645892
,
160647701
,
160969514
,
162172236
,
164045359
,
164194090
,
164824489
,
165245531
,
170498903
,
171578894
,
172091286
,
174477515
,
175266472
,
175427064
,
175610897
,
177748765
,
178103004
,
180189087
,
185985285
,
198991713
|
|
ChEBI ID | CHEBI:68579 | |
ADReCS Drug ID | BADD_D01954 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |