Drug ID: D01035

Drug General Information

Drug Name
Ticagrelor
Synonyms
Ticagrelor; 274693-27-5; Brilique; AZD-6140; AZD6140; AZD 6140; AR-C126532XX; UNII-GLH0314RVC; [14C]-Ticagrelor; GLH0314RVC; CHEBI:68558; (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-DIFLUOROPHENYL)CYCLOPROPYL]AMINO]-5-(PROPYLTHIO)-3H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-3-YL]-5-(2-HYDROXYETHOXY)-1,2-CYCLOPENTANEDIOL; (1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; Brilique; AR-C126532; Ticagrelor (USAN/INN); Brilinta/Brilique
Drug Type
Small molecular drug
Company
AstraZeneca
Summary
Ticagrelor is a P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.

Drug Chemical Infomation and External Links

Download MOL File
Formula
C23H28F2N6O4S
Canonical SMILES
CCCSC1=NC(=C2C(=N1)N(N=N2)C3CC(C(C3O)O)OCCO)NC4CC4C5=CC(=C(C=C5)F)F
InChI
1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1
InChIKey
OEKWJQXRCDYSHL-FNOIDJSQSA-N
CAS Number CAS 274693-27-5
TTD ID D0WF7L
DrugBank ID DB08816
PubChem Compound ID 9871419
PubChem Substance ID
14836432 , 14860737 , 24162024 , 45293678 , 49684205 , 57373617 , 77877844 , 92729712 , 96025700 , 103554312 , 123051091 , 124759706 , 126644885 , 126666051 , 135649975 , 136345665 , 137171656 , 139857160 , 152040158 , 152258075 , 160645837 , 160646914 , 162011636 , 163346229 , 163383616 , 164178089 , 164765598 , 165245536 , 170501033 , 171063069 , 172914585 , 174528632 , 175267325 , 175427101 , 185974765 , 189657701 , 198993342 , 211534943 , 223384813 , 223666650 , 224638556 , 228139491 , 247988848 , 249582784 , 249807649 , 249807650 , 249816423 , 251966736 , 251970939 , 252216468
ChEBI ID CHEBI:68558
ADReCS Drug ID BADD_D02214

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification