Drug General Information
| Drug Name |
Ivermectin
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| Synonyms |
I 8898; Ivexterm (TN); MK-933; Mectizan (TN); Stromectol (TN)
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| Drug Type |
Small molecular drug
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| Indications |
Intestinal strongyloidiasis due to nematode parasite [ICD-11: 1F6B]
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Approved
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| Company |
Merck & Co
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| Summary |
Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
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| Target |
Onchocerca Glutamate-gated chloride channel (Onchoc GluCl)
Mechanism of Action: Activator
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T16047 | |
Drug Chemical Infomation and External Links
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Formula |
C48H74O14
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| Canonical SMILES |
CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
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| InChI |
1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
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| InChIKey |
AZSNMRSAGSSBNP-XPNPUAGNSA-N
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| CAS Number | CAS 71827-03-7 | |
| TTD ID | D09YHJ | |
| DrugBank ID | DB00602 | |
| PubChem Compound ID | 6321424 | |
| PubChem Substance ID | ||
| ChEBI ID | CHEBI:63941 | |
| ADReCS Drug ID | BADD_D01221 |
Drug-Food (Herb) Interactions
- Drug
- Foods
- Herbs
- Positive
- Negative
- Possible
- Harmful
- No Effect
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |