Drug Name |
Lisinopril
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Synonyms |
Acerbon; Acercomp; Alapril; Carace; Cipral; Cipril; Coric; Doneka; Hipril (TN); Inhibril; Inopril; LPR; Linopril; Linvas; Lipril; Lisinal; Lisinopril (INN); Lisinopril (anhydrous); Lisinopril anhydrous; Lisinoprilum; Lisinoprilum [Latin]; Lisipril; Lisoril; Lispril; Longes; Loril; Lysinopril; MK 521; MK 522; MK-521; Noperten; Novatec; Presiten; Prinil; Prinivil; Prinivil (TN); Sinopril; Sinopryl; Tensopril; Tensopril (TN); Tensyn; Tersif; Vivatec; Zestril; Zestril (TN)
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Drug Type |
Small molecular drug
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Indications |
Hypertension [ICD-11: BA00-BA04]
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Approved
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Company |
Merck & Co
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Summary |
Lisinopril is an ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
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Target |
Angiotensin-converting enzyme (ACE)
Mechanism of Action: Inhibitor
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T82577 |
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Formula |
C21H31N3O5
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Canonical SMILES |
C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O
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|
InChI |
1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1
|
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InChIKey |
RLAWWYSOJDYHDC-BZSNNMDCSA-N
|
|
CAS Number | CAS 76547-98-3 | |
TTD ID | D07HGR | |
DrugBank ID | DB00722 | |
PubChem Compound ID | 5362119 | |
PubChem Substance ID |
7888691
,
7979780
,
8149783
,
10322439
,
11336212
,
11361451
,
11363391
,
11365953
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11368515
,
11372101
,
11374737
,
11376677
,
11462423
,
11466329
,
11467449
,
11485087
,
11486217
,
11489272
,
11490756
,
11492854
,
11494311
,
11654003
,
12013163
,
14806092
,
14830773
,
25622282
,
26612244
,
26680616
,
26697064
,
39384398
,
46504893
,
47515403
,
47515404
,
47810844
,
47885506
,
47885507
,
48035230
,
49698425
,
49835323
,
50019882
,
50085996
,
50124344
,
53787084
,
56311259
,
57362085
,
78195378
,
81066263
,
85787499
,
87560323
,
92124278
|
|
ChEBI ID | CHEBI:43755 | |
ADReCS Drug ID | BADD_D01300 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |