Drug ID: D00824

Drug General Information

Drug Name
Terbinafine
Synonyms
Bramazil; Lamasil; TerbiFoam; Terbina; Lamisil AT; Lamisil Tablet; Ternbinafine HCl; Lamasil (TN); Lamisil (TN); SF 86-327; Terbisil (TN); Zabel (TN); SF-86-327; Terbinafine (USAN/INN); Terbinafine [USAN:BAN:INN]; Lamisil, Terbinex, Corbinal, Zabel, Terbinafine; Terbinafine, SF-86-327, Lamisil, TBNF; (2E)-N,6,6-trimethyl-N-(1-naphthylmethyl)-2-hepten-4-yn-1-amine; (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine; (E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine; (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine; (E)-N-(6,6-dimethyl-2-heptenynyl)-N-methyl-1-naphthalenementhamin hydrochloride
Drug Type
Small molecular drug
Indications
Onychomycosis [ICD-11: EE12.1]
Phase 2
Fungal infection [ICD-11: 1F29-1F2F]
Approved
Company
Celtic Pharma
Summary
Terbinafine is an allylamine antifungal used to treat dermatophyte infections of toenails and fingernails as well as other fungal skin infections.
Target
Candida Squalene epoxidase (Candi ERG1)
Mechanism of Action: Modulator
 T78173

Drug Chemical Infomation and External Links

Download MOL File
Formula
C21H25N
Canonical SMILES
CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21
InChI
1S/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+
InChIKey
DOMXUEMWDBAQBQ-WEVVVXLNSA-N
CAS Number CAS 91161-71-6
TTD ID D01AYJ
DrugBank ID DB00857
PubChem Compound ID 1549008
PubChem Substance ID
10279 , 606886 , 3206272 , 7849434 , 7980758 , 8653314 , 14800096 , 26754460 , 29215261 , 32248932 , 46508519 , 48416599 , 49995731 , 50593794 , 53790235 , 56313213 , 57288850 , 57409064 , 85279511 , 90452133 , 92308716 , 92711333 , 93166983 , 93625488 , 103215995 , 103929637 , 104253338 , 105999123 , 110525170 , 124757457 , 124766229 , 124899382 , 125093510 , 125164261 , 125325631 , 126571952 , 126630967 , 126657418 , 126664777 , 126831911 , 131330035 , 134338039 , 135014005 , 135692246 , 137003885 , 142367778 , 144205144 , 162179180 , 164786802 , 170465174
ChEBI ID CHEBI:9448
ADReCS Drug ID BADD_D01241

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification