Drug Name |
Deferasirox
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Synonyms |
Deferasirox
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Drug Type |
Small molecular drug
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Company |
Novartis
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Summary |
Deferasirox is an iron chelator used to treat chronic iron overload caused by blood transfusions. Also used in patients with non-transfusion-dependent thalassemia syndromes, and in patients with elevated liver iron concentration and serum ferritin.
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Formula |
C21H15N3O4
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Canonical SMILES |
C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
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InChI |
1S/C21H15N3O4/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28/h1-12,25-26H,(H,27,28)
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InChIKey |
BOFQWVMAQOTZIW-UHFFFAOYSA-N
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CAS Number | CAS 201530-41-8 | |
TTD ID | D0Q5UQ | |
DrugBank ID | DB01609 | |
PubChem Compound ID | 214348 | |
PubChem Substance ID |
14853198
,
17397765
,
29157338
,
39475182
,
46506791
,
49693590
,
50070193
,
50071321
,
50362477
,
53787326
,
57364789
,
104179183
,
104253329
,
114000977
,
124757448
,
124772227
,
125164252
,
126592965
,
126666897
,
135129477
,
137008102
,
137248684
,
143497484
,
144115893
,
144206479
,
151995258
,
152236475
,
160964846
,
162188004
,
170464723
,
175266885
,
179117014
,
184545799
,
186022468
,
223384180
,
223663416
,
226443599
,
241050655
,
251892008
,
252219959
,
252390148
,
252471362
|
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ChEBI ID | CHEBI:49005 | |
ADReCS Drug ID | BADD_D00594 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |