Drug ID: D00727

Drug General Information

Drug Name
Migalastat
Synonyms
DDIG; D-Galactitol, 1,5-dideoxy-1,5-imino; (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol; 1,5-Dideoxy-1,5-iminogalactitol; 2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
Drug Type
Small molecular drug
Indications
Fabry disease [ICD-11: 5C56.01]
Approved
Company
Amicus Therapeutics
Summary
Migalastat is an alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
Target
Alpha-galactosidase A (GLA)
Mechanism of Action: Modulator
 T21678

Drug Chemical Infomation and External Links

Download MOL File
Formula
C6H13NO4
Canonical SMILES
C1C(C(C(C(N1)CO)O)O)O
InChI
1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5+,6-/m1/s1
InChIKey
LXBIFEVIBLOUGU-DPYQTVNSSA-N
CAS Number CAS 108147-54-2
TTD ID D0MU9L
DrugBank ID DB05018
PubChem Compound ID 176077
PubChem Substance ID
796556 , 10258334 , 11114003 , 15066543 , 15321768 , 33499767 , 34884209 , 50069796 , 76308781 , 103329495 , 104049440 , 104425300 , 128553861 , 131271591 , 131481001 , 131481032 , 134348144 , 135154287 , 137263801 , 139879276 , 144203290 , 144221323 , 162774201 , 172232452 , 178483437 , 198184004 , 198975997 , 223733290 , 227686116 , 249807450 , 250135145
ChEBI ID CHEBI:135923
ADReCS Drug ID NA

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification