Drug Name |
Bazedoxifene
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Synonyms |
Brilence; Conbriza; Viviant; Bazedoxifene acetate; TSE-424; WAY-140424; WAY-TES 424
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Drug Type |
Small molecular drug
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Indications |
Osteopetrosis [ICD-11: LD24.10]
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Approved
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|
Company |
Ligand Pharmaceuticals Inc
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Summary |
Bazedoxifene is a selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens.
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Target |
Estrogen receptor (ESR)
Mechanism of Action: Modulator
|
T89534 |
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Formula |
C30H34N2O3
|
Canonical SMILES |
CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OCCN4CCCCCC4)C5=CC=C(C=C5)O
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InChI |
1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3
|
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InChIKey |
UCJGJABZCDBEDK-UHFFFAOYSA-N
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|
CAS Number | CAS 198481-32-2 | |
TTD ID | D0JY8T | |
DrugBank ID | DB06401 | |
PubChem Compound ID | 154257 | |
PubChem Substance ID |
5417414
,
10252039
,
14907497
,
46230413
,
50409595
,
103224092
,
103996451
,
104438324
,
125669539
,
129348176
,
135129358
,
137115372
,
142033963
,
160647805
,
162810855
,
163621139
,
175267431
,
178103927
,
179150132
,
185964861
,
198992700
,
204379955
,
223780042
,
226426848
,
251971047
,
252434487
,
252477814
|
|
ChEBI ID | CHEBI:135947 | |
ADReCS Drug ID | BADD_D00215 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |