Drug Name |
Moexipril
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Synonyms |
Moexiprilum; Uniretic; Moexipril (INN); Moexipril [INN:BAN]; Moexiprilum [INN-Latin]; Perdix (TN); Univasc (TN); (3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-6,7-bis(methyloxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
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Drug Type |
Small molecular drug
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Indications |
Hypertension [ICD-11: BA00-BA04]
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Approved
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|
Company |
Ucb Inc
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Summary |
Moexipril is an angiotensin converting enzyme inhibitor prodrug used to treat hypertension.
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Target |
Angiotensin-converting enzyme (ACE)
Mechanism of Action: Inhibitor
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T82577 |
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Formula |
C27H34N2O7
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Canonical SMILES |
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC
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|
InChI |
1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1
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InChIKey |
UWWDHYUMIORJTA-HSQYWUDLSA-N
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|
CAS Number | CAS 103775-10-6 | |
TTD ID | D00HDU | |
DrugBank ID | DB00691 | |
PubChem Compound ID | 91270 | |
PubChem Substance ID |
9906
,
7980014
,
10224695
,
14884255
,
14933223
,
44422239
,
46508441
,
48416289
,
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,
51009191
,
85789110
,
93166165
,
96024913
,
103339306
,
103831006
,
103984203
,
104404350
,
117576966
,
126683035
,
129432080
,
134222210
,
134337877
,
135049415
,
135153605
,
137003828
,
141323944
,
143493279
,
151982736
,
152164600
,
152238590
,
160964036
,
162178212
,
164786738
,
172914179
,
175266162
,
178103185
,
179149500
,
184545955
,
223440353
,
223653409
,
224369399
,
226420555
,
252390154
|
|
ChEBI ID | CHEBI:6960 | |
ADReCS Drug ID | BADD_D01485 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |