Drug ID: D00597

Drug General Information

Drug Name
Atorvastatin
Synonyms
Atogal; Atorlip; Atorpic; Atorvastatina; Atorvastatine; Atorvastatinium; Atrovastin; Cardyl; Faboxim; Lipotropic; Lipovastatinklonal; Liprimar; Lowden; Sincol; Sortis; Sotis; Torvacard; Torvast; Totalip; Tozalip; Tulip; Vastina; Xanator; Xarator; Xavator; Zurinel; Atorvastatin (INN); Atorvastatin [INN:BAN]; Lipitor (TN); Lipitor(TM); Sortis (TN); (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; (R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid; (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid; 7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
Drug Type
Small molecular drug
Indications
Cardiovascular disease [ICD-11: BA00-BE2Z]
Approved
Company
Pfizer Pharmaceuticals
Summary
Atorvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Target
HMG-CoA reductase (HMGCR)
Mechanism of Action: Inhibitor
 T53585

Drug Chemical Infomation and External Links

Download MOL File
Formula
C33H35FN2O5
Canonical SMILES
CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
InChI
1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1
InChIKey
XUKUURHRXDUEBC-KAYWLYCHSA-N
CAS Number CAS 134523-00-5
TTD ID D01QIN
DrugBank ID DB01076
PubChem Compound ID 60823
PubChem Substance ID
9052 , 822166 , 7884979 , 7978735 , 8187078 , 14910832 , 26684326 , 26697359 , 29215408 , 43118161 , 49845979 , 50037926 , 51091801 , 53787715 , 56311281 , 56311722 , 56311943 , 56311969 , 56312802 , 56313042 , 56313334 , 56313578 , 56314463 , 57314133 , 75432172 , 85856289 , 92714388 , 93166494 , 103554720 , 104178840 , 104321734 , 104829550 , 117367061 , 124892211 , 126525305 , 126624171 , 126658151 , 126682126 , 127315782 , 127315783 , 127315784 , 127315785 , 127315786 , 127315787 , 127315788 , 127315789 , 127315790 , 127315791 , 127315792 , 127315793
ChEBI ID CHEBI:39548
ADReCS Drug ID BADD_D00182

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification