Drug ID: D00583

Drug General Information

Drug Name
Ranolazine
Synonyms
RANOLAZINE; 95635-55-5; Ranexa; N-(2,6-dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide; CVT-303; (-)-Ranolazine; Ranolazine (Ranexa); Ranolazine 2HCl; RS-43285-003; 142387-99-3; N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide; CHEBI:87690; N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide; C24H33N3O4; NCGC00015897-02; DSSTox_RID_80743; DSSTox_CID_25196; DSSTox_GSID_45196; Ran4; CVT 303; Latixa; RAN D; Latixa; Ranolazine dihydrochloride; KEG-1295; RS-43285; Ranexa (TN); Ranexa, Ranolazine; Ranolazine (USAN/INN); Ranolazine extended-release; Ranolazine/Dronedarone Fixed-Dose Combination
Drug Type
Small molecular drug
Indications
Chronic/stable angina [ICD-11: BA40.1]
Approved
Paroxysmal atrial fibrillation [ICD-11: BC81.30]
Phase 2
Company
CV Therapeutics
Summary
Ranolazine is an anti-anginal drug used for the treatment of chronic angina.
Target
Plasminogen (PLG)
Mechanism of Action: Modulator
 T89034

Drug Chemical Infomation and External Links

Download MOL File
Formula
C24H33N3O4
Canonical SMILES
CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O
InChI
1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
InChIKey
XKLMZUWKNUAPSZ-UHFFFAOYSA-N
CAS Number CAS 95635-55-5
TTD ID D03HYQ
DrugBank ID DB00243
PubChem Compound ID 56959
PubChem Substance ID
7980486 , 8184974 , 12013498 , 14856376 , 26612929 , 26749060 , 26749061 , 43114706 , 46505145 , 47207361 , 47795040 , 48169373 , 50070803 , 50107515 , 51004683 , 56463697 , 57313861 , 81040983 , 85171832 , 85789241 , 90340842 , 92124680 , 92307911 , 92309225 , 92712119 , 103482101 , 104171232 , 104253386 , 104311416 , 117573069 , 121363701 , 124750209 , 124757504 , 124799345 , 124881338 , 124881339 , 125164308 , 125360240 , 126583887 , 126622101 , 126630205 , 126656915 , 126666839 , 126724363 , 129701807 , 134338152 , 135015431 , 135684171 , 135692283 , 136375567
ChEBI ID CHEBI:87690
ADReCS Drug ID BADD_D01915

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification