Drug General Information
| Drug Name |
Ribavirin
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| Synonyms |
ribavirin; 36791-04-5; Tribavirin; Rebetol; Virazole; Ribavirine; Copegus; Vilona; Ribamide; Ribasphere; Ribamidil; Viramid; Ribamidyl; Ribavirinum; Ribavirina; Rebetron; Varazid; RTCA; Ribavirin Capsules; Ribavirinum [INN-Latin]; Ribavirine [INN-French]; Ribavirina [INN-Spanish]; ICN-1229; Rebretron; Virazid; Ribav; 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide; DRG-0028; 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; UNII-49717AWG6K; Ribavirin (Copegus); Copegus; Cotronak; RBV; RTC; Ravanex; Ribacine; Ribovirin; Viramide; Virazide; R 9644; SCH 18908; C-Virin; Copegus (TN); Drug: Ribavirin; KS-1104; R-964; RG-964; Rebetol (TN); Ribasphere (TN); Ribavirin [USAN:INN]; Vilona (TN); Virazole (Ribavirin) Inhalation Solution; Virazole (TN); AA-504/07617051; Ro 20-9963/000; Ro-20-9963; Ribavirin (JAN/USP/INN); 1-beta-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide; 1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide; RBI034 (2-5A antisense compound) + Ribavirin
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| Drug Type |
Small molecular drug
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| Indications |
Hepatitis C virus infection [ICD-11: 1E51.1]
|
Approved
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|
| Company |
Hoffmann-La Roche pharmaceutical company
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| Summary |
Ribavirin is a guanosine nucleoside used to treat some forms of Hepatitis C.
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| Target |
Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1)
Mechanism of Action: Inhibitor
|
T40111 | |
Drug Chemical Infomation and External Links
|
Formula |
C8H12N4O5
|
| Canonical SMILES |
C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N
|
|
| InChI |
1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
|
|
| InChIKey |
IWUCXVSUMQZMFG-AFCXAGJDSA-N
|
|
| CAS Number | CAS 36791-04-5 | |
| TTD ID | D0H3WI | |
| DrugBank ID | DB00811 | |
| PubChem Compound ID | 37542 | |
| PubChem Substance ID |
595938
,
7847489
,
7980513
,
8139972
,
8150084
,
8175073
,
11335957
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,
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12059582
,
14798456
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17389529
,
17405619
,
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,
25621753
,
26538475
,
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,
26679740
,
34678832
,
46505883
,
47291173
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47365228
,
47440296
,
47515344
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47885447
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,
48035157
,
48416516
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48424047
,
48425596
,
48631153
,
49699015
,
50105410
,
50105411
,
50105412
,
50105413
,
50474786
,
53778169
|
|
| ChEBI ID | CHEBI:63580 | |
| ADReCS Drug ID | BADD_D01933 |
Drug-Food (Herb) Interactions
- Drug
- Foods
- Herbs
- Positive
- Negative
- Possible
- Harmful
- No Effect
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |