| Drug Name |
Galantamine
|
||
| Synonyms |
GNT; Galantamin; Galantamina; Galantaminum; Galanthamine; Galanthaminum; Jilkon; Lycoremin; Lycoremine; Reminyl; Razadyne ER; Galantamina [INN-Spanish]; Galantamine [USAN:INN]; Galantaminum [INN-Latin]; Nivalin (TN); Razadyne (TN); Razadyne ER (TN); Reminyl (TN); Galantamine (USAN/INN); (-)-Galanthamine; (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro(3a,3,2-ef)(2)benzazepin-6-ol
|
||
| Drug Type |
Small molecular drug
|
||
| Indications |
Alzheimer disease [ICD-11: 8A20]
|
Approved
|
|
| Company |
Janssen Pharmaceutica
|
||
| Summary |
Galantamine is a cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease.
|
||
| Target |
Acetylcholinesterase (AChE)
Mechanism of Action: Inhibitor
|
T30082 | |
|
Formula |
C17H21NO3
|
| Canonical SMILES |
CN1CCC23C=CC(CC2OC4=C(C=CC(=C34)C1)OC)O
|
|
| InChI |
1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1
|
|
| InChIKey |
ASUTZQLVASHGKV-JDFRZJQESA-N
|
|
| CAS Number | CAS 357-70-0 | |
| TTD ID | D0R9VR | |
| DrugBank ID | DB00674 | |
| PubChem Compound ID | 9651 | |
| PubChem Substance ID |
10719
,
584656
,
584664
,
606095
,
831251
,
7887946
,
7979350
,
8004402
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8156932
,
11335765
,
11361004
,
11364165
,
11366727
,
11369289
,
11372735
,
11374555
,
11377451
,
11461976
,
11466616
,
11467736
,
11486391
,
11491553
,
11492654
,
11495085
,
11537759
,
14751181
,
14775584
,
24875119
,
25646023
,
26697250
,
26751839
,
29228225
,
46391750
,
46393027
,
46505659
,
46511027
,
47206224
,
47216757
,
47216758
,
47291111
,
47515304
,
47588978
,
47885390
,
47959724
,
48259212
,
48334469
,
48334470
,
49698570
,
49972082
,
53786839
|
|
| ChEBI ID | CHEBI:42944 | |
| ADReCS Drug ID | BADD_D00996 |
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |