Drug General Information
| Drug Name |
Primaquine
|
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| Synonyms |
Kanaprim; Primachin; Primachina; Primachinum; Primaquin; Primaquina; Primaquinum; Primachina [DCIT]; SN 13272; WR 2975; Dl-Primaquine; Kanaprim (TN); Neo-Quipenyl; Primaquina [INN-Spanish]; Primaquine (INN); Primaquine Bis-Phosphoric Acid; Primaquine [INN:BAN]; Primaquinum [INN-Latin]; SN 13,272; TG1-296; TG1-297; Ethylbutylamino)-6-methoxyquinoline; S. N. 13272; N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine; Quinoline, 8-(4-amino-1-methylbutylamino)-6-methoxy; N(4)-(6-methoxyquinolin-8-yl)pentane-1,4-diamine; N-(5-aminopentan-2-yl)-6-methoxyquinolin-8-amine; N~4~-[6-(methyloxy)quinolin-8-yl]pentane-1,4-diamine; Quinoline, 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-(6CI,8CI); (+)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine; (+)-Primaquine; (+/-)-Primaquine; (-)-N4-(6-Methoxy-8-quinolinyl)-1,4-pentanediamine; (-)-Primaquine; 1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-(9CI); 4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine; 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline; 6-Methoxy-8-[(4-amino-1-methylbutyl)amino]quinoline; 6-Methoxy-8-[4-amino-1-methylbutylamino]quinoline; 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinoline; 8-(4-Amino-1-m; 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline; 8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline
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| Drug Type |
Small molecular drug
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||
| Indications |
Malaria [ICD-11: 1F40-1F45]
|
Approved
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|
| Company |
Sanofi-Aventis
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| Summary |
Primaquine is an antimalarial indicated to prevent relapse of vivax malaria.
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| Target |
Plasmodium Deoxyribonucleic acid (Malaria DNA)
Mechanism of Action: NA
|
T20089 | |
Drug Chemical Infomation and External Links
|
Formula |
C15H21N3O
|
| Canonical SMILES |
CC(CCCN)NC1=C2C(=CC(=C1)OC)C=CC=N2
|
|
| InChI |
1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3
|
|
| InChIKey |
INDBQLZJXZLFIT-UHFFFAOYSA-N
|
|
| CAS Number | CAS 90-34-6 | |
| TTD ID | D0T1LK | |
| DrugBank ID | DB01087 | |
| PubChem Compound ID | 4908 | |
| PubChem Substance ID |
9829
,
87834
,
598065
,
602722
,
604501
,
5227598
,
7980381
,
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11335981
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11361220
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,
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,
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,
11462192
,
11466504
,
11467624
,
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,
11486287
,
11488703
,
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,
11492299
,
11494644
,
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,
24715072
,
24715073
,
29223986
,
46508222
,
47291261
,
47291262
,
47291263
,
47440410
,
47885557
,
47959923
,
47959924
,
48035284
,
48110597
,
48416468
,
49698880
,
50042258
,
50123426
,
50123427
,
50725468
,
53790596
,
56312914
|
|
| ChEBI ID | CHEBI:8405 | |
| ADReCS Drug ID | BADD_D01838 |
Drug-Food (Herb) Interactions
- Drug
- Foods
- Herbs
- Positive
- Negative
- Possible
- Harmful
- No Effect
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |