Drug ID: D00291

Drug General Information

Drug Name
Phenacetin
Synonyms
phenacetin; 62-44-2; Acetophenetidin; N-(4-Ethoxyphenyl)acetamide; Acetphenetidin; Acetophenetidine; Acetophenetin; Phenacetine; p-Acetophenetidide; Contradouleur; Commotional; Achrocidin; Phenazetin; Contradol; Codempiral; 4'-Ethoxyacetanilide; 4-Ethoxyacetanilide; Acetamide, N-(4-ethoxyphenyl)-; p-Acetophenetidine; Fenacetina; Phenidin; Pyraphen; Phenacitin; Phenacetinum; Fenidina; Phenedina; Phenacet; Pertonal; Fenina; Phenin; Kalmin; p-Acetphenetidin; p-Acetophenetide; Phenazetina; Tetracydin; p-Ethoxyacetanilide; Stellacyl; Phenodyne; Imidazo[4,5-e][1,4]diazapine nucleotide (I)
Drug Type
Small molecular drug
Indications
Analgesia [ICD-11: MB40.8]
Withdrawn from market
Company
NA
Summary
Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy (damage to or disease of the kidney).
Target
Prostaglandin G/H synthase 1 (COX-1)
Mechanism of Action: Inhibitor
 T60529
Inosine-5'-monophosphate dehydrogenase 1 (IMPDH1)
Mechanism of Action: Inhibitor
 T40111

Drug Chemical Infomation and External Links

Download MOL File
Formula
C10H13NO2
Canonical SMILES
CCOC1=CC=C(C=C1)NC(=O)C
InChI
1S/C10H13NO2/c1-3-13-10-6-4-9(5-7-10)11-8(2)12/h4-7H,3H2,1-2H3,(H,11,12)
InChIKey
CPJSUEIXXCENMM-UHFFFAOYSA-N
CAS Number CAS 62-44-2
TTD ID D0O2IE
DrugBank ID DB03783
PubChem Compound ID 4754
PubChem Substance ID
9793 , 73483 , 841972 , 3139201 , 3724298 , 7348354 , 7847635 , 8147859 , 8149602 , 8152917 , 10321803 , 10530552 , 11112166 , 11335755 , 11360994 , 11363676 , 11366238 , 11368800 , 11372367 , 11374228 , 11376962 , 11461966 , 11466561 , 11467681 , 11485715 , 11486202 , 11489756 , 11491219 , 11492330 , 11494596 , 12016023 , 14748329 , 16962413 , 17389770 , 22388565 , 24858936 , 24887192 , 24890660 , 26611996 , 26679408 , 26747350 , 26747351 , 26752986 , 26752987 , 29223838 , 36018734 , 46507394 , 47440229 , 47959721 , 48035093
ChEBI ID CHEBI:8050
ADReCS Drug ID NA

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification