Drug ID: D00263

Drug General Information

Drug Name
Nisoldipine
Synonyms
Baymycard; Nisocor; Nisoldipin; Nisoldipino; Nisoldipinum; Sular; Syscor; Zadipina; Bay k 5552; Nisoldipino [INN-Spanish]; Nisoldipinum [INN-Latin]; Sular (TN); Bay-k-5552; Nisoldipine (JAN/USAN/INN); Nisoldipine [USAN:BAN:INN:JAN]; Isobutyl 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(2-nitrophenyl)-3-pyridincarboxylat;Methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; (+-)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, methyl 2-methylpropyl ester; 3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Drug Type
Small molecular drug
Indications
Hypertension [ICD-11: BA00-BA04]
Approved
Company
NA
Summary
Nisoldipine is a calcium channel blocker used as monotherapy or combined with other drugs for the treatment of hypertension.
Target
Calcium channel unspecific (CaC)
Mechanism of Action: Blocker
 T45993

Drug Chemical Infomation and External Links

Download MOL File
Formula
C20H24N2O6
Canonical SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
InChI
1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3
InChIKey
VKQFCGNPDRICFG-UHFFFAOYSA-N
CAS Number CAS 63675-72-9
TTD ID D0S5CU
DrugBank ID DB00401
PubChem Compound ID 4499
PubChem Substance ID
9901 , 5054384 , 6595685 , 6951250 , 7594280 , 7847684 , 7980129 , 8152772 , 11528722 , 12012773 , 14780577 , 26719878 , 26758055 , 29223593 , 46386699 , 46504546 , 48416330 , 49681768 , 53787999 , 56313694 , 56463094 , 57322301 , 80626920 , 81092916 , 92307945 , 92308528 , 92308896 , 92711446 , 93166842 , 103219831 , 103680984 , 104306583 , 117875317 , 118048486 , 121363368 , 124658895 , 124799896 , 125355226 , 126630843 , 126657331 , 126665640 , 131322121 , 131846259 , 134337886 , 135004762 , 135650722 , 135692260 , 137122027 , 137349418 , 139157574
ChEBI ID CHEBI:76917
ADReCS Drug ID BADD_D01570

Drug-Food (Herb) Interactions

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  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification