Drug ID: D00260

Drug General Information

Drug Name
Nilutamide
Synonyms
Anandron; Nilandron; Nilandrone; Nilutamida; Nilutamidum; Aventis Behring Brand of Nilutamide; Aventis Brand of Nilutamide; Hoechst Brand of Nilutamide; Nilutamida [Spanish]; Nilutamidum [Latin]; N 8534; RU 23908; Anandron (TN); RU 23908-10; RU-23908; Nilutamide (USAN/INN); Nilutamide [USAN:BAN:INN]; Nilutamide [USAN:INN:BAN]; 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione; 5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione; 5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin; 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione; 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione; 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
Drug Type
Small molecular drug
Indications
Prostate cancer [ICD-11: 2C82.0]
Approved
Company
Aventis Pharmaceuticals Inc.
Summary
Nilutamide is an antineoplastic hormone used to treat prostate cancer.
Target
Androgen receptor (AR)
Mechanism of Action: Antagonist
 T11211

Drug Chemical Infomation and External Links

Download MOL File
Formula
C12H10F3N3O4
Canonical SMILES
CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
InChI
1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChIKey
XWXYUMMDTVBTOU-UHFFFAOYSA-N
CAS Number CAS 63612-50-0
TTD ID D0SN9T
DrugBank ID DB00665
PubChem Compound ID 4493
PubChem Substance ID
10364 , 5851647 , 7404097 , 7848028 , 7978498 , 8152766 , 11111555 , 11111556 , 11114201 , 11342173 , 11362356 , 11364519 , 11367081 , 11369643 , 11372644 , 11374239 , 11377805 , 11466956 , 11468076 , 11485861 , 11486751 , 11487758 , 11489789 , 11491448 , 11492415 , 11495439 , 12013485 , 14850346 , 17405438 , 24278596 , 26612639 , 26680190 , 26747174 , 26747175 , 26752242 , 29223587 , 46505381 , 47365306 , 47365307 , 47959867 , 48110544 , 48259346 , 48259347 , 48334600 , 49698835 , 49980214 , 50104947 , 50104948 , 50104949 , 50104950
ChEBI ID CHEBI:7573
ADReCS Drug ID BADD_D01568

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification