Drug ID: D00207

Drug General Information

Drug Name
Lamotrigine
Synonyms
Crisomet; Labileno; Lamictal; Lamictin; Lamiktal; Lamitor; Lamotrigina; Lamotriginum; Desitin Brand of Lamotrigine; Faes Brand of Lamotrigine; Glaxo Wellcome Brand of Lamotrigine; GlaxoSmithKline Brand of Lamotrigine; Juste Brand of Lamotrigine; Lamictal Cd; Lamictal ODT; Lamictal XR; Lamotrigina [Spanish]; Lamotriginum [Latin]; BW 430C; GI 267119X; GW 273293; L 3791; BW-430C; EUR-1048; Lamictal (TN); Lamictin (TN); Lamotrigine [USAN:INN:BAN]; Lamotrigine (JAN/USAN/INN); 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine; 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine; 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diyldiamine; 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Drug Type
Small molecular drug
Indications
Epilepsy [ICD-11: 8A60-8A68]
Approved
Bipolar disorder [ICD-11: 6A60]
Approved
Company
GSK
Summary
Lamotrigine is a phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder.
Target
Voltage-gated sodium channel alpha Nav1.9 (SCN11A)
Mechanism of Action: Blocker
 T34123

Drug Chemical Infomation and External Links

Download MOL File
Formula
C9H7Cl2N5
Canonical SMILES
C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
InChI
1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChIKey
PYZRQGJRPPTADH-UHFFFAOYSA-N
CAS Number CAS 84057-84-1
TTD ID D03FLC
DrugBank ID DB00555
PubChem Compound ID 3878
PubChem Substance ID
855818 , 5669156 , 7847420 , 7979720 , 8152444 , 11111377 , 11113342 , 11528749 , 12013463 , 14823602 , 17405249 , 24278792 , 26719658 , 29222992 , 46386680 , 46505408 , 47810853 , 48259345 , 48416154 , 50100261 , 50104089 , 50104090 , 53777794 , 53787568 , 56423136 , 57322032 , 58107296 , 76843584 , 81092819 , 85231112 , 90341162 , 91148150 , 92304062 , 92308151 , 92308280 , 92308924 , 92709766 , 93166952 , 103199382 , 103940000 , 104179107 , 104304778 , 111978157 , 117872151 , 121361621 , 124658861 , 124799528 , 124880544 , 124880545 , 124880546
ChEBI ID CHEBI:6367
ADReCS Drug ID BADD_D01243

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification