Drug ID: D00199

Drug General Information

Drug Name
Isocarboxazid
Synonyms
BMIH; Benazide; Enerzer; Isocarbonazid; Isocarbossazide; Isocarboxazida; Isocarboxazide; Isocarboxazidum; Isocarboxyzid; Maraplan; Marplan; Marplon; Isocarbossazide [DCIT]; Isocarboxazid (INN); Isocarboxazid [INN:BAN]; Isocarboxazida [INN-Spanish]; Isocarboxazide [INN-French]; Isocarboxazidum [INN-Latin]; Marplan (TN); Ro5-0831; Ro 5-0831/1; N'-Benzyl N-methyl-5-isoxazolecarboxylhydrazide-3; N'-benzyl-5-methyl-1,2-oxazole-3-carbohydrazide; 1-Benzyl-2-(5-methyl-3-isoxazolyl-carbonyl)hydrazine; 1-Benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine; 3-Isoxazolecarboxylic acid, 5-methyl-, 2-(phenylmethyl)hydrazide; 3-Isoxazolecarboxylic acid, 5-methyl-, 2-benzylhydrazide; 5-Methyl-3-isoxazolecarboxylic acid 2-benzylhydrazide; 5-methyl-N'-(phenylmethyl)isoxazole-3-carbohydrazide
Drug Type
Small molecular drug
Indications
Depression [ICD-11: 6A70-6A7Z]
Approved
Company
Hoffmann-La Roche pharmaceutical company
Summary
Isocarboxazid is a monoamine oxidase inhibitor used to treat enduring and debilitating symptoms of depression following inadequate clinical response to other antidepressant drugs.
Target
Monoamine oxidase type A (MAO-A)
Mechanism of Action: Inhibitor
 T83875

Drug Chemical Infomation and External Links

Download MOL File
Formula
C12H13N3O2
Canonical SMILES
CC1=CC(=NO1)C(=O)NNCC2=CC=CC=C2
InChI
1S/C12H13N3O2/c1-9-7-11(15-17-9)12(16)14-13-8-10-5-3-2-4-6-10/h2-7,13H,8H2,1H3,(H,14,16)
InChIKey
XKFPYPQQHFEXRZ-UHFFFAOYSA-N
CAS Number CAS 59-63-2
TTD ID D0I2VK
DrugBank ID DB01247
PubChem Compound ID 3759
PubChem Substance ID
442485 , 4667752 , 8152378 , 10528879 , 11112152 , 11466823 , 11467943 , 11486605 , 16885460 , 17396751 , 29222879 , 46505330 , 47365381 , 48185156 , 48185157 , 48334685 , 48416130 , 49699170 , 49987628 , 50100378 , 50591995 , 56463226 , 57321980 , 58106974 , 85789365 , 92125896 , 99358097 , 103771151 , 103914493 , 104231731 , 104304439 , 121363567 , 124799381 , 124881991 , 126646731 , 134337868 , 134972611 , 136214439 , 137002954 , 139640708 , 144203887 , 160825711 , 160964579 , 163092606 , 163389007 , 163842003 , 172908333 , 175267943 , 175612006 , 178103779
ChEBI ID CHEBI:93635
ADReCS Drug ID BADD_D01202

Drug-Food (Herb) Interactions

  • Drug
  • Foods
  • Herbs
  • Positive
  • Negative
  • Possible
  • Harmful
  • No Effect
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship Classification
ID Name Dose Type Drug Brand Name Drug Dose Drug Dosage Form Experimental Species Individuals Number Test Sample Ingredient Effect Relationship classification