Drug General Information
| Drug Name |
Clonidine
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| Synonyms |
clonidine; Clonidin; Duraclon; Chlornidinum; 4205-90-7; Catapres-TTS; Catarpresan; Catarpres; Adesipress; Catapres; Catapressan; Catapresan; ST 155BS; ST-155-BS; Clonidinum; Clonidina; Clonidinum [INN-Latin]; Clonidinhydrochlorid; CATAPRES-TTS-3; CATAPRES-TTS-1; CATAPRES-TTS-2; N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine; Isoglaucon; 2-(2,6-Dichloroanilino)-2-imidazoline; Dixarit; SKF 34427; Catapres- TTS; Clonidina [INN-Spanish]; M-5041T; Hemiton; CLORPRES; clonidine (amino form); Adesipress; Clofenil; Clopheline; Duraclont; Gemiton; Klofelin; Klofenil; M 5041T; Catapres (TN); Catarpres-TTS; ST-155BS; Tenso-Timelets; Catarpres-TTS (TN); Clonidine [USAN:BAN:INN]; Clonidine (JAN/USAN/INN); 1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro-(9CI); 2,6-Dichloro-N-2-imidazolidinylidenebenzenamine; 2,6-dichloro-N-(2-imidazolidinylidene)aniline; 2,6-dichloro-N-2-imidazolidinylidenebenzenamide; 2,6-dichloro-N-imidazolidin-2-ylideneaniline; 2-((2,6-Dichlorophenyl)imino)imidazolidine; 2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2);2-(2,6-Dichloroanilino)-2-imidazoline; 2-(2,6-Dichlorophenylamino)-2-imidazoline; 2-(2,6-Dichlorophenylimino)imidazolidine; 2-Imidazoline, 2-(2,6-dichloroanilino)-(7CI,8CI); 2-[(2,6-Dichlorophenyl)imino]imidazoline; 2-[(2,6-dichlorophenyl)imino]-2-imidazoline; 734571A; 2,6-DICHLORO-N-IMIDAZOLIDIN-2-YLIDENEANILINE
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| Drug Type |
Small molecular drug
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| Indications |
Hypertension [ICD-11: BA00-BA04]
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Approved
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|
|
Diabetic neuropathy [ICD-11: 8C0Z]
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Phase 3
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| Company |
Intas Pharmaceuticals
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| Summary |
Clonidine is an alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
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| Target |
Adrenergic receptor Alpha-2 (ADRA2)
Mechanism of Action: Agonist
|
T31424 | |
|
Membrane copper amine oxidase (AOC3)
Mechanism of Action: Inhibitor
|
T69619 | ||
Drug Chemical Infomation and External Links
|
Formula |
C9H9Cl2N3
|
| Canonical SMILES |
C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl
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|
| InChI |
1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)
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|
| InChIKey |
GJSURZIOUXUGAL-UHFFFAOYSA-N
|
|
| CAS Number | CAS 4205-90-7 | |
| TTD ID | D03SKR | |
| DrugBank ID | DB00575 | |
| PubChem Compound ID | 2803 | |
| PubChem Substance ID |
840960
,
841959
,
4807400
,
5991864
,
7847347
,
7978974
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8151812
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,
26697416
,
26697467
,
26751841
,
26751842
,
29221958
,
46508119
,
47216577
|
|
| ChEBI ID | CHEBI:3757 | |
| ADReCS Drug ID | BADD_D00502 |
Drug-Food (Herb) Interactions
- Drug
- Foods
- Herbs
- Positive
- Negative
- Possible
- Harmful
- No Effect
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |