Drug Name |
Buspirone
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Synonyms |
Ansial; Ansiced; Anxiron; Axoren; Bespar; Buspirona; Buspironum; Buspisal; Ansial (TN); Ansiced (TN); Anxiron (TN); Axoren (TN); Bespar (TN); BuSpar (TN); Buspimen (TN); Buspinol (TN); Buspiron (TN); Buspirona [INN-Spanish]; Buspirone (INN); Buspirone [INN:BAN]; Buspirone-MDTS; Buspironum [INN-Latin]; Buspisal (TN); Gen-Buspirone; Narol (TN); Sorbon (TN); Spamilan (TN); Spitomin (TN); Gen-Buspirone (TN); MJ-9022-1; N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-1-cyclopentanediacetamide; 8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione; 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione; 8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione
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Drug Type |
Small molecular drug
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||
Indications |
Anxiety disorder [ICD-11: 6B00-6B0Z]
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Approved
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|
Company |
Bristol-Myers Squibb
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Summary |
Buspirone is an anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
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Target |
5-HT 1A receptor (HTR1A)
Mechanism of Action: Agonist
|
T78709 |
|
Formula |
C21H31N5O2
|
Canonical SMILES |
C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4
|
|
InChI |
1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
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|
InChIKey |
QWCRAEMEVRGPNT-UHFFFAOYSA-N
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|
CAS Number | CAS 36505-84-7 | |
TTD ID | D0U2OO | |
DrugBank ID | DB00490 | |
PubChem Compound ID | 2477 | |
PubChem Substance ID |
9079
,
4652644
,
7978828
,
8151653
,
10589701
,
11110857
,
11112732
,
11113821
,
11336096
,
11361335
,
11364650
,
11367212
,
11369774
,
11377936
,
11462307
,
11466397
,
11467517
,
11486154
,
11495570
,
11533496
,
14902734
,
24714738
,
25671043
,
26751994
,
29221641
,
46508113
,
47365265
,
47365266
,
47440338
,
47589062
,
47662354
,
48259310
,
48259311
,
48259312
,
48415667
,
49698848
,
49872682
,
50104669
,
51066541
,
51091905
,
53790629
,
57321342
,
85209802
,
85787807
,
85788842
,
90340780
,
92309215
,
93166677
,
103166970
,
103916226
|
|
ChEBI ID | CHEBI:3223 | |
ADReCS Drug ID | BADD_D00316 |
ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
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ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |