Drug General Information
| Drug Name |
Alprazolam
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| Synonyms |
Alcelam; Algad; Alpaz; Alplax; Alpram; Alprax; Alprazolamum; Alprazolan; Alpronax; Alprox; Alviz; Alzam; Alzolam; Alzon;Anpress; ApoAlpraz; Azor; Bestrol; Cassadan; Constan; Esparon; Frontal; Helex; Intensol; Ksalol; Mialin; Neurol; Niravam; NovoAlprazol; NuAlpraz; Panistat; Panix; Pharnax; Prazam; Prazolan; Prinox; Ralozam; Relaxol; Restyl; Solanax; Tafil; Tensivan; Tranax; Trankimazin; Tranquinal; Tricalma; Unilan; Valeans; Xanagis; Xanax; Xanolam; Xanor; Zacetin; Zanapam; Zaxan; Zenax; Zolam; Zolan; Zolarem; Zoldac; Zoldax; Zopax; Zopic; Zotran; Alphapharm Brand of Alprazolam; Alprazolam Alphapharm Brand; Alprazolam Apotex Brand; Alprazolam Kenral Brand; Alprazolam Novopharm Brand; Alprazolam Orion Brand; Alprazolam Pfizer Brand; Alprazolam Temmler Brand; Alprazolam extended release tablets; Alprazolam intensol; Alprazolam solution; Apo Alpraz; Apotex Brand of Alprazolam; Arzneimittelwerk Dresden Brand of Alprazolam; Kenral Brand of Alprazolam; Novo Alprazol; Novopharm Brand of Alprazolam; Nu Alpraz; Nu Pharm Brand of Alprazolam; Orion Brand of Alprazolam; Pfizer Brand of Alprazolam; Tafil D; Temmler Brand of Alprazolam; Xanax TS; Xanax XR; D 65MT; D65MT; TGAR01P; Tus 1; U 31889; AP-1002; AZ-002; Alprazolam Nu-Pharm Brand; Alprazolam-d5; Alprazolamum [INN-Latin]; Apo-Alpraz; D-65MT; Gen-Alprazolan; Niravam (TN); Novo-Alprazol; Nu-Alpraz; Nu-Pharm Brand of Alprazolam; Staccato-alprazolam; TUS-1; U-31889; U31,889; Xanax (TN); Xanor (TN); U-31,889; Alprazolam (JP15/USP/INN); Alprazolam [USAN:INN:BAN:JAN]; 8-Chloro-1-methyl-6-(phenyl-d5)-4H-(1,2,4)triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-alpha)(1,4)benzodiazepine; 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
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| Drug Type |
Small molecular drug
|
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| Indications |
Anxiety disorder [ICD-11: 6B00-6B0Z]
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Approved
|
|
|
Epilepsy [ICD-11: 8A60-8A68]
|
Phase 2
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| Company |
Pfizer Pharmaceuticals
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| Summary |
Alprazolam is a triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
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| Target |
Translocator protein (TSPO)
Mechanism of Action: Agonist
|
T75440 | |
Drug Chemical Infomation and External Links
|
Formula |
C17H13ClN4
|
| Canonical SMILES |
CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
|
|
| InChI |
1S/C17H13ClN4/c1-11-20-21-16-10-19-17(12-5-3-2-4-6-12)14-9-13(18)7-8-15(14)22(11)16/h2-9H,10H2,1H3
|
|
| InChIKey |
VREFGVBLTWBCJP-UHFFFAOYSA-N
|
|
| CAS Number | CAS 28981-97-7 | |
| TTD ID | D0L9GG | |
| DrugBank ID | DB00404 | |
| PubChem Compound ID | 2118 | |
| PubChem Substance ID |
9035
,
866237
,
7403853
,
7847292
,
7849651
,
7978675
,
8151436
,
10517236
,
12013413
,
14742608
,
14800856
,
22396017
,
24882050
,
24891103
,
24891366
,
26719699
,
29215419
,
29215420
,
29221298
,
46386679
,
46507078
,
48415537
,
50057265
,
50823025
,
53790970
,
56313723
,
57321151
,
57651813
,
57653873
,
81093308
,
92308240
,
92716916
,
93166633
,
93167168
,
93620403
,
103189284
,
103916140
,
104299658
,
109613253
,
117786302
,
124658860
,
125347118
,
126622623
,
126651409
,
126723170
,
129515347
,
131309066
,
134221861
,
134337553
,
134997022
|
|
| ChEBI ID | CHEBI:2611 | |
| ADReCS Drug ID | BADD_D00085 |
Drug-Food (Herb) Interactions
- Drug
- Foods
- Herbs
- Positive
- Negative
- Possible
- Harmful
- No Effect
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship Classification | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Name | Dose | Type | Drug Brand Name | Drug Dose | Drug Dosage Form | Experimental Species | Individuals Number | Test Sample | Ingredient | Effect | Relationship classification |